Funds will be donated via Canceragogo, a California Corporation, is an approved 501C3 charity, via check or bank wire (bank wire instructions available upon request).
Canceragogo, Suite E212, 200 Clock Tower Place, Carmel, CA 93923
Attorney for charity: Anthony Karachale. Horan – Lloyd, Carmel, CA.
CPA: Chris Steinbrunner, SteinHill, Carnel, CA
Funds to reside in Union Bank of Carmel.
Alternatively Funds could be set up as a draw from benefactor’s assigned account, using checks and bank wires.
We have organized the perfect advisory board.
Dr. Sam Cheshier
Dr. Robert Wechsler Reya
Dr. Sabine Mueller
Dr. Michael Taylor
Dr. Carl June
Dr. Giselle Sholer
Dr. Sylvain Martel
Meryl Witmer (Eagle Capital, Berkshire Hathaway)
Jenna Fisher (Russell Reynolds)
Dr. Alex Huang
Dr. Rich Vile
Dr John Letterio
Dr. Michael Taylor
Dr. Christine Brown
Dr. Siddhartha Mitra
Dr. Duane Mitchell
Dr. Mark Souweidane
Dr. Crystal Mackall
“Giant leaps in technology have made a cure imminent for so many different pediatric cancers,” says Dr Sam Cheshier, a Stanford pediatric neurosurgeon and esteemed researcher, who heads McDowell’s advisory committee. “I believe $250 million, if used creatively in pursuit of a cure, could bring an end to pediatric brain cancer once and for all.”
Step 1-10.
1. Comprehensive Tumor Acquisition: Make patient derived tumor lines from ALL patients
Post op and post mortem (DIPG)
Will set up program to solicit the cooperation of Surgeons, oncologist, neuropathology, coroners.
2. Comprehensive Characterization of ALL patient samples
- Subtyping Cancer type
- Subtyping immune phenotype
- Whole Genome Sequencing (DNA mutation)
- RNAseq Analysis (gene expression profiling)
- Clinically driven protein expression profiling
3. Assign/set up: Translational Pediatric Neuro Oncology Center(s) to test ALL tumors against ALL FDA approved drugs.
4. Translational Pediatric Neuro Oncology Center(s) to test ALL tumors against ANY investigative drug.
5. Translational Pediatric Neuro Oncology Center(s) to explore ANY potential treatment derived from the Comprehensive Characterization
6. Translational Pediatric Neuro Oncology Center(s) for preclinical testing of ALL promising therapies against ALL tumors in vitro and in vivo, Non immune therapies, Immune therapies, combinations
- Standard Research Method
- Democratic Research Method
7. Investigator Initiated Trials
- New agents directed toward pediatric brain cancers.
- Existing agents redirected toward pediatric brain cancers.
8. Award Genius Grants
9. Full time coordinator
10. Fund via key Brain Cancer organizations.
11. Publicist updating parents and families, linking to our website with up to the minute treatment options and science.