Study raises hopes of treating aggressive cancers by zapping rogue DNA
Tumours could be reduced by targeting genetic material driving their growth with a new drug in early-stage trials
Scientists have raised hopes of treating some of the most aggressive cases of cancer by targeting small fragments of rogue DNA that help tumours thrive and become resistant to chemotherapy……
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Breast cancer drug could help prolong survival for children with brain tumors, study finds
A 10-year-old girl who took the drug lived for 17 months with no disease progression
Published September 6, 2024 – A drug called ribociclib, currently used to treat breast cancer, could slow the progression of certain pediatric high-grade gliomas, ……
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Thank you to Nature Medicine for publication of this commentary (click here) on the market failures associated with inadequate drug development, and how the Give Kids a Chance Act, HR 6972 would provide that novel combinations of therapies developed for adults with cancer are studied in children with cancer as well.
Dear Friends:
We did it. Thank you.
The RACE for Children Act will be fully implemented.
Read More….
Letter from a dad.
The short courageous life of Santiago Estevez.
FAVORITES
– Potential cancer breakthrough: Scientists develop a drug that can block cancer-causing gene | Daily Mail Online
– Potential cancer breakthrough as terminal patients see tumors shrink or stop growing after being treated with a virus | Daily Mail Online
– From Dr. Sheila Singh, pediatric neurosurgeon, McMaster University – November 28th, 2022
– Life-Saving Breakthrough for Antibiotics Uses Shapeshifting Chemistry that Won 2022 Nobel Prize – May 3, 2023
– This Gel Stops Brain Tumors After Surgery, Offering Hope for Glioblastoma Cancer Patients By Good News Network – April 30, 2023
– Dr. Sheila Singh, pediatric neurosurgeon-researcher, McMaster University
– Israeli scientists kill cancer cells with ground-breaking DNA-altering treatment they compare to using ‘microscopic scissors’ to target tumors | Daily Mail Online
– Congress passed the STAR Act! May 2018 | Children’s Cause Cancer Advocacy
– Cancer therapy shows promise for some brain tumor | The Inquirer – Philly.com
– A 150-year-old drug might improve radiation therapy for cancer | Science Daily
– Tiny molecule has big effect in childhood brain tumor studies | Science Daily
– A 150-year-old drug might improve radiation therapy for cancer | Science Daily
– Antibiotics HALVE life expectancy of cancer sufferers, NHS medics reveal in world first at US conference | Daily Mail Online
– New cancer vaccine can teach the immune system to ‘see’ rogue cells | Daily Mail Online
– First HIV immunotherapy drug proves safe in phase 1 trial | Daily Mail Online
– Pediatric Cancers: New Bill Seeks to Close Clinical Trial Requirement Loopholes | RAPS
– A new treatment aims to prevent hair loss in cancer patients | CNBC
– Potential treatment for brain cancer as drug shrinks tumours | Medical Xpress
– Cancer Commons finds Personalized Treatment Options for Cancer that has Spread. | Cancer Commons
– We Just Found a Game-Changing Weapon Against Drug-Resistant Superbugs | Science Alert
– Pipeline a new modality for the treatment of cancer | VYRIAD – Pipeline
– UPDATES ON p53
– Startup with Johns Hopkins roots raising $40.5 million to develop cancer metabolism drugs | endpoints news
– Another Cancer Vaccine Shows Promise In Mice | USNews.com
– New skin cancer jab is created by British scientists who have even identified how to predict which patients it can save | Daily Mail Online
– Talazoparib Significantly Extends Progression-Free Survival in Phase 3 EMBRACA Trial of Patients with Metastatic Breast Cancer | Pfizer Inc.
– Cancer ‘vaccine’ eliminates tumors in mice | News Center | Stanford Medicine
– Eradication of spontaneous malignancy by local immunotherapy | Science Translational Medicine
– Blood test detects cancers in up to 98% of sufferers | Daily Mail Online
– FDA approves first drug for women with breast cancer caused by the ‘Jolie gene’ | Daily Mail Online
– Breakthrough Study: Virus Injected Into Blood Attacks Brain Cancer, Stimulates Immune System | Study Finds
– Stephen Tait – Mitochondria and Cell Death | Cancer Research UK
– A Christmas miracle: Mother-of-two, 35, given four years to live is breast cancer-free after taking a revolutionary drug and said she can finally ‘dare to dream’ | Daily Mail Online
– MicroRNA-206 inhibits the viability and migration of medulloblastoma cells by targeting LIM and SH3 protein 1 | US National Library of Medicine National Institutes of Health
– 4SC-202 as a Potential Treatment for the Pediatric Brain Tumor Medulloblastoma | Brain Sciences
– Scientists ‘completely CURE’ bowel cancer in mice using a form of pioneering immunotherapy and say it could kill ‘virtually ALL’ tumor types | Daily Mail Online
– Students Supporting Brain Tumor Research – ssbtr.org
– Boosting immunotherapy by targeting cells’ recycling centers | FierceBiotech
– ‘Hit-and-run’ gene therapy nanoparticles could enhance CAR-T treatments | FierceBiotech
– Two potential boosters for improving checkpoint inhibition in cancer | FierceBiotech
– IMPACT (IMproving Patient Access to Cancer Clinical Trials) | Lazarex Cancer Foundation
– Parker Institute for Cancer Immunotherapy | Sean Parker
– Arizona Enacts Law: Pharmaceutical Companies to Legally Communicate Off-Label Treatment to Medical Professionals – Policy and Medicine
– Anti-cancer breakthrough CICD can eradicate tumours, researchers say – Sky News
– This protein is mutated in half of all cancers. New drugs aim to fix it before it’s too late | Science | AAAS
– Focused Ultrasound and Cancer Immunotherapy
– New Approach in T-cell Therapy to Treat Cancer – ScienceNewsline
– Successfully Treating Genetically Determined Autoimmune Enteritis – ScienceNewsline
– Newly Enlisted T-cell ‘Policemen’ Can Slow Down Run-away Immune System, SLU Scientist Says – ScienceNewsline
– Wasp Venom Selectively Assassinates Cancer Cells – Discover Magazine
– Companies Rush to Develop ‘Utterly Transformative’ Gene Therapies – NY Times
– F.D.A. Panel Recommends Approval for Gene-Altering Leukemia Treatment | NYTimes
– Report: Early Trials of ‘Cancer Vaccines’ Were ‘Safe and Effective’ Attacking Tumors – Breitbart
– Chemotherapy could cause cancer to spread, NY study says | Daily Mail Online
– New insight into medulloblastoma | The Brain Tumour Charity
– Antibiotics and vitamin C could kill cancer cells | Daily Mail Online
– Scientists hail blood test that detects cancer years ahead of symptoms – Times of Malta
– Prostate cancer trial stuns researchers: ‘It’s a once in a career feeling’ – Society | The Guardian
– ‘This is not the end’: Using immunotherapy and a genetic glitch to give cancer patients hope – The Washington Post
– Breakthrough in cancer research could spawn new treatments – CNN
– Cancer Vaccine ImMucin Shows Promising Results After Clinical Trial – Vaxil Bio
– Breakthrough: Treating cancer with new proton beam therapy – Building a Better World
– More Effective Immunotherapy For Cancer – Memorial Sloan Kettering Cancer Center
– With New Name and $86M, Tioma To Explore Anti-CD47 Cancer Therapy – xconomy.com
– Cancer breakthrough: Scientists kill ‘undruggable’ protein – Daily Mail Online
– VBI Vaccines Announces Medulloblastoma Immunotherapy Program
– Ultrasound Implant Safely Opens Blood–Brain Barrier – Scientific American
– Toca 5 Brain Cancer Clinical Trial: Enrollment is Now Open
– Daily Mail Online – Why processed food may cause bowel cancer
– The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCd-dependent inhibition of the AKT pathway
– OnPAR: A Second Chance for Unfunded NIH Proposals
– The Drug Virtually Everyone Should Ask their Doctor About – Life Extension
– anh-usa.org
– Are we nearing a cure for cancer?
– ‘Bubble boy’ gene therapy raises hope – Harvard Gazette
– ‘Amazing’ new breast cancer drugs could extend life of sufferers – Telegraph
– Immunotherapy Offers Hope to Brain Tumor Patients – njtv online
– Terminal patients could be saved by ‘exciting’ new treatment – dailymail.co.uk
– Repurposing Drugs in Oncology (ReDO) – NIH – National Institutes of Health
– The cancer drugs in your bathroom cabinet – the Guardian
– Device Uses Ultrasound to Achieve Permeability of Blood Vessels in Brain
– How liquid aspirin could help fight brain cancer
– Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma. – PubMed – NCBI
– Review of the pemetrexed and gemcitabine combination in patients with advanced-stage non-small cell lung cancer
– The cancer killers
– New Vaccine Helps Prevent Brain Tumors From Coming Back
– Buck Rogers and the amazing death stalker scorpion
– ScienceDaily – Compounds in parsley and dill help fight cancer, research shows
– Cancer Vaccine ImMucin Shows Promising Results After Clinical Trial
– Metronomic and Targeted Anti-angiogenesis Therapy for Children With Recurrent/Progressive Medulloblastoma – ClinicalTrials.gov
– Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity
– New drugs and methods of altering a patient’s own immune cells are helping some cancer patients — but not all — even when standard treatments fail.
– First gene-editing trial to start next month in China
– Cancer Science – Medulloblastoma stem cells: Promising targets in medulloblastoma therapy
– Daily Mail Online – Scientists create single treatment that could provide life-long cure for a host of diseases
– Mirror Online – Doctors wake coma patient by JUMP-STARTING his brain using ultrasound
– Cancerworld – Too affordable: how can we overcome the drug repurposing paradox?
– Daily Mail Online – Microsoft is aiming to ‘solve’ cancer using computer science
– Fastercures.org
– CFF Therapeutics Lab, Bethesda, MD
– Safety Data for Lirilumab in Combination with Nivolumab or Ipilimumab Announced at ESMO 2016 Congress – Nachricht
– miles for hope
– Daily Mail Online – Game-changing immunotherapy drug DOUBLES head and neck cancer survival rates
– Worm pills a safer alternative for cancer? at Cancer Forum, topic 123844
– Cancer patients and their loved ones.
– Every professional on our list of beneficiaries.
– Doctors.
– Nurses.
– Researchers.
– Acupuncture to restore ototoxic hearing loss.
– Rolfing, extraordinarily restorative body work.
– Hospital Staff, Valet car parkers, Kitchen and Janitor staff.
– Kind people
– Taxpayers for funding the National Institute of Health (NIH)
– Volunteers
– Jansen Pharma
– Sean Parker
– Sandy and Joan Weill
– Daniel Ludwig
– Phil and Penelope Knight
– Mark Zuckerberg
– Priscilla Chan
– James Stowers
– Dave Sabey
– Leidos’s brilliant “OnPar” program.